For around 20 years, scientists have been studying green-lipped mussels as a safe and effective alternative for dogs (and people) who can’t take NSAIDs (non-steroidal anti-inflammatories).
The Green Lipped Mussel contains a powerhouse of Omega-3 fatty acids DHA (docosahexaenoic acid) and EPA (eicosapentaenoic acid), minerals including, zinc, copper, manganese and the key antioxidant vitamins - E and C.
EPA and DHA from Green Lipped Mussel have been scientifically proven to proactively down-regulate COX-2 expression, which is an inflammatory mediator.
Osteoarthritis is created by a ‘self-perpetuating’ inflammatory cycle, caused by ‘inflammatory mediators’ that stimulate the production of more inflammatory mediators.
NSAIDs are routinely prescribed as they are known to break this cycle by inhibiting these mediators, and most notably, the COX-2 enzyme. (Laflamme 2012).
However long-term use of NSAIDS can cause side effects from vomiting, and lethargy, to kidney and liver disease (Bren 2006).
Unlike NSAIDs, green-lipped mussels are rich in glycosaminoglycans (or GAGs). An important GAG found in GLM is chondroitin sulfate.
Chondroitin strengthens your dog’s joint capsules and this allows them to hold more water. More water means more shock absorption leading to less wear and tear on the joints. It means that GLM not only reduces arthritic symptoms but also helps restore your dog’s joints!
Also, unlike NSAIDs, GLM contains LOX (lipoxygenase) inhibitors. These enzymes protect the stomach lining and liver from harm.
Plus, research shows green-lipped mussels keep delivering these health benefits, even a full month after you stop giving them to your dog!