Guest Blog: Dr Conor Brady
Cancer in dogs is on the rise, but why? Here Dr Conor Brady gives you a wealth of information on the causes and preventions too. A must read!
With all the chemical and plastic junk we have injected into our environment and food chain, it's little wonder humans are now one of the most cancer stricken animals on the planet. We are in fact in second place, juuusssstt behind dogs...and by “just” I mean they've lapped us TEN TIMES.
Yes, somewhat unbelievably, as good as we try to be for them – the best of kibble and veterinary care, monthly parasite prevention, annual boosters, all the things we are told to do to preserve their health – these incredibly weak creatures still manage to be approximately ten times more likely to get cancer than us humans. Isn't that staggering? 5,300/100,000 pampered pooches in America each year are diagnosed with cancer compared to just 500/100,000 Americans.
Now to make that a touch worse, we now know that 90-95% of cancer today is not genetic, it is driven by environmental and lifestyle factors. As the saying goes, genes may load the gun but environment pulls the trigger. For example, you can be prone to lung cancer but if you don't smoke you are more likely to get away with it.
In short, it's us that's doing it to them. Something we are putting on or in (or around) our dogs is tripping the cancer switches.
Diet plays a very significant role in the development of cancer, with poor quality fats (kibble), ultra-processed meat (kibble) and too much salt (kibble) among the chief protagonists but no one food group affects us more than and too much refined carbohydrates (kibble, kibble kibble).
To get a better understanding as to why (and why they need to be avoided in the dog with cancer), I've given you below an excerpt from my book Feeding Dog (*Please note: for the scientists among you, I have removed all but the last references I used in order to make the passage easier to read):
“Tumours are total carb / sugar junkies. In fairness, all cells need sugar to operate but cancer cells use glucose at 10-20 times the rate of normal cells. Their high sugar-uptake is actually the main way we look for them, using a method called a PET-CT (Positron Emission Tomography and Computed Tomography) scan. PET scans use radioactively labelled glucose to detect sugar-hungry tumour cells. When patients drink the sugar water, the mix gets preferentially taken up by the cancer cells and they light up. This helps physicians see where it is, to evaluate the extent of the disease, to deduce which treatments to use and to check if those treatments are working. In fact, all the way back in 1931 Otto Warburg won the Nobel Prize for his discovery that cancer cells have a different energy metabolism to healthy cells, notably a greater rate of glycolysis (the process of converting glucose to energy) compared with normal cells.
In this way, a high sugar diet and cancer are the best of friends, but the relationship goes much deeper than that. Macrophage-mediated programmed cell removal (PrCR), or phagocytosis for short, plays an essential role in tumour surveillance and elimination. These are the seek, engulf and destroy cells of the immune system. We’ve known since 1971 that just 100g of sugar via sucrose, honey or orange juice significantly reduces phagocytosis in humans and the effect can last up to five hours. If you’re a cancer cell thinking of getting up to mischief, this is most welcome.
It gets worse. As more and more sugar is consumed, cell-resistance to insulin builds, meaning more and more insulin is released into the blood. Insulin is a powerful stimulant of cell growth as it drives fuel into the cell. Cancer cells have 10-20 times the insulin receptors of normal cells which enables them to gorge on glucose. In this way, excess sugar leading to obesity and high blood insulin is an important factor in cancer.
These insulin receptors are everywhere in your body. Hence too much sugar, coupled with excess insulin, is now firmly linked to the development of cancer of the breast, ovaries, pancreas, biliary tract, lung, gallbladder, stomach and colorectal cancer of humans.
Tavani et al. (2006) studied 2,569 women with breast cancer and 2,588 females without. They found a direct association between breast cancer risk and sugar consumption, a result of an increase in insulin and insulin growth factors. Unsurprisingly, the advice for humans with mammary tumours is to reduce the carbohydrate / sugar content of your diet.
It happens that mammary tumours are the most frequently diagnosed neoplasm in intact female dogs. What’s more, dogs are known to suffer mammary cancer at least 2 to 3 times the rate of humans. The incidence of breast cancer in human females is currently around 12% worldwide. On their website in 2017, the American College of Veterinary Surgeons states the that the risk of a female dog developing a mammary tumour is “0.5% if bitches are spayed before their first heat (approximately 6 months of age), 8% after their first heat, and 26% after their second heat”. That’s 1 in 4 intact adult female dogs (the ACVS go on to state that while 50% of mammary tumours are benign and 50% are malignant though thankfully few of the malignant mammary tumours are fatal).
As we know mammary gland tumours share common features between dogs and humans, with authors noting dogs make excellent models for the development, prognosis and treatment of breast cancer in humans, does it not follow that a high carbohydrate diet and permanently high blood insulin will plays a significant role in this the most common cancer of dogs?!
I’ll save you the suspense - we have known for more than 20 years that reducing carbohydrates in the diet prevents tumour growth in dogs. The author notes that dogs with cancer are proven to do significantly better on diets containing less carbohydrates.”
It surely goes without saying that cancer is complicated. You can be on the best diet, which surely increases your chances, but you can still get unlucky. The reason being there are a number of horrible products and lifestyle choices out there that can fuel such a diagnosis. Below I deal with the top five.
Go keto - feed a fresh diet higher in fat, moderate protein and virtually zero carbs.
For those confused as to how much of which think fatty beef mince in the shops which is slightly more fat than protein (say 25% fat, 20% protein, the rest being water). When we look at this via metabolisable energy (ME) lens, important for keto, we fat offers around 2.5times the energy than protein, equating to a ME ratio of nearly 3:1. This is where you want to be for keto.
Recommended meat ingredients
We still work with the rough 70:10:10:10 ratio (meaning lots of meat, 10% bone, 10% organ, some plant matter for their bioactive compounds) but your mixes should now be made with higher fat red meats such as beef, pork, duck, oily fish, maybe lamb depending on the pieces used (chicken and turkey don't have the oomf and you'll be running around looking for fat additions). Mussels and eggs are great additions here too.
It's important that your meats are now as good as possible. This means outdoor reared, organic, all that stuff. Studies show intensively reared meat, particularly chicken, is inflammatory to dogs, albeit this is a US study, a mix of the antibiotics used, that reside in the bones of the bird and the high omega 6 content of the meat from the grain diet.
Organic, outdoor-reared meat contains much more omega 3 so using such meat means we have to think less about the omega 3:6 ratio which, with a cancer diagnosis is important. We now aim to fight inflammation by keeping the amount of omega 3 up (and 6 down) in our diet. Omega 6 comes from veg oils so we now avoid these in cancer dogs. If you had to use one though (say to increase the fat content of a lean meal) something like coconut oil is fine, lower in omega 6 and full of MCT (medium chain triglycerides) which the body loves.
Common question 1 – should dogs with cancer eat raw dog food? First off, if your dog is going through chemo and you're heavily stressed, don't give this a seconds thought. Feed him lightly cooked food. But as soon as that dog comes home, contrary to what you hear on many vet websites (that also claim you shouldn't feed fresh food to healthy cats and dogs...), the answer is almost certainly yes to fresh food. All human patients living with cancer need fresh food, it's part of their recovery. Good quality raw dog food is one of the cleanest, most nutrient dense substrates you can now feed your pet....particularly when for comparison we have kibble – a product beset with microbiological contamination, recalled regularly for not only Salmonella but also containing cancer-causing nasties such as mycotoxins and this is before we talk about its other cancer-causing issues such as ultra-processed protein, poor quality fats, high salt content, conical flask nutrients, lack of bioactive compounds, myriad of chemicals, anti-life which napalms the gut flora, the fact it's bad for teeth which spikes inflammation. Above all, multiple studies now prove it is highly inflammatory to dogs.
There are no perfect options here guys. You can only do your best and the best is real food. Don't let them sell you otherwise.
Common question 2 – how much and how often should you feed a dog with cancer?
The answer is really whatever he needs. As this is a higher fat diet, he will not need as much, say around 2% of his body weight per day and adjust from there. If he is guts are not in good order (or he is losing weight), he will need more.
How often is important. We now know we are eating too much and too often. It takes an enormous amount of energy to process a meal. That's why you feel tired and yawn after large meals. It takes 16hrs to process that meal – 8hrs to digest and assimilate it and another 8hrs to pack it all away. The noble prize was awarded recently to scientists that showed after 16hrs of not eating your body goes into autophagy (something like housekeeping). No longer distracted with digestion, it begins to zap cancer cells. This is why we advise dogs with cancer get 1 or 2 meals and those two meals shouldn't be more than 6hrs apart. This is termed intermittent fasting. More on that here.
The veg I recommend are chosen for their cancer-fighting properties. They include spinach and kale (folate), broccoli sprouts (get used to growing your own, broccoli sprouts contain all sorts but they are particularly high in cancer-fighting sulfrofane, 100-400 times as much as normal cruciferous veg!), tomato puree (lycopene, cooked tomato has more than raw!), celery (luteolin), zucchini (manganese). I steam there to make them easier to digest. Give the water they're cooked in too (contains any good bits that fell out!).
While we urge you to avoid fruit for now (sugar) wild berries are simply too important to ignore and, thankfully, are low in sugar. Check out Loov online – wild bilberry and sea buckthorn, shaken from trees in the forest. Deeply nutritious and full of polyphenols and anthocyanins, potent antioxidants and proven highly anti-cancerous in studies). Just a dusting, very beneficial.
Paleo Plus Berry Good is Supplement containing Wild Berries.
You must remove all sources of sugar including rice, potatoes, pasta, starch-rich veg such as peas, carrots and potatoes and fruit. Feed them like a carnivore to starve tumour growth.
No more packet food or treats. We need to avoid all chemical preservatives. Make your own meat-based treats!
There has never been a better time to go natural. You need to reconsider your use of everything. First to go are all the chemical flea and worm treatments and unecessary boosters. We don't have time to get into it now but suffice to say your dog has bigger problems right now than the parasites he doesn't have! And they say rather the parasites than the chemicals used to prevent them. We don't dose our kids with these things and you needn't use them on your dog, necessarily. Please read up on the natural approach to the aforementioned “threats”:.
You also need to get rid of those poisonous lawn chemicals. Studies show our little sniffers are particularly susceptible to them on a cancer-front.
Next turn your attention to inside your house. Plug in air fresheners, sprays, scented candles, all of them can be a problem. What are you cleaning your floor in? Still using chemical anti-life?! That has to go. Now's the time to jump to probiotic floor cleaners. Now, instead of trying to kill the baddies (which only lasts while the product is wet, once dry it blows away) you layer good guys on your surfaces which sit there and outcompete the bad guys. Isn't that amazing? You can use them on your floors, surfaces, bathrooms, everywhere. Even hospitals are now taking this approach. Check out the results from this Italian hospital. Truly incredible. I recommend Ingenious Probiotics in the UK for a list of these sorts of info and products. Great company.
That'll do start guys. Most of the above can be done in conjunction with a move conventional approach. In fact, concepts like great food are essential to their recovery. Please discuss any and all concerns and feeding regimes with your vet (ideally one that has studies nutrition – the ones not recommending high carbohydrate dry food for your pet...). Please visit the RFVS website for a list of vets that can help you in that regard, many are but a Zoom consult away.
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